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Actos is a prescribed medication used as a remedy for type 2 diabetes. The curing effect of Actos is based on its ability to improve insulin sensitivity and thus lower the level of blood sugar and control it easier. As the drug lowers the level of blood sugar it consequently helps to reduce the risk of developing long-term problems caused by and related to diabetes, for instance heart disease or diabetic nephropathy. It is also capable of provoking side effects, such as upper respiratory infection, headache, and sinus infection.
What Is Actos And What Is It Used for
Actos (pioglitazone hydrochloride) is a drug available on prescription and used in the course of type 2 diabetes treatment (aka noninsulin-dependent diabetes or adult-onset diabetes). There is a possibility of using Actos alone, or it might be combined with other diabetes medications. However, it is not suitable to be used as a remedy for the type 1 diabetes.
Who Manufactures Actos?
Actos is currently produced by Takeda Pharmaceutical Company.
In What Way Does Actos Work?
Actos belongs to the thiazolidinediones, or, as they are sometimes called, "glitazones" group of medicines. It acts by improving insulin sensitivity, which consequently promotes your body to better use its natural insulin. Thus the level of blood sugar is lowered and then easier kept under control. Several lab studies have been carried out to estimate the effectiveness of Actos for type 2 diabetes.
How Effective is Actos?
Actos and Hemoglobin A1c
Hemoglobin A1c (HbA1c) is a test which shows the long-term blood sugar control. For those not suffering from diabetes, its results are usually below 6 percent, when those who have diabetes the results are higher. One of the studies showed that people taking Actos were able to lower their HbA1c by up to 0.9 percent. For those not undergoing the therapy the figures showed the increase of HbA1c by 0.7 percent.
According to the research that the higher the HbA1c is, the more risk of developing long-term problems with diabetes like for instance heart disease, diabetic retinopathy, diabetic neuropathy, and diabetic nephropathy exists. The chances of getting these diabetes-caused dysfunctions are lowered if the level of blood sugar is controlled by means of taking Actos.
Fasting Blood Sugar and Actos
Fasting blood sugar is another type of the test to find out how effective a diabetes medication is. The data shows that the people taking Actos managed to decrease their fasting blood sugar index by 30 to 56 mg/dL, while those not undergoing the therapy faced the opposite effect.
Other Effects of Actos
Actos made people taking it gain about two to nine pounds. It might also affect the levels of HDL cholesterol and LDL cholesterol.
How Do I Take Actos?
Here is the usual instruction on how and when Actos should be taken:
- Actos is produced in pills for oral intake once a day.
- Actos intake does not depend on the intake of food. If you feel discomfort after taking it on empty stomach, you might as well try taking it along with a meal.
- Do make your intake of Actos regular. To maintain the equal concentration of the drug in your blood take your daily dose at the same time.
- Do not violate the rules of prescription or stop the therapy, because otherwise it would not produce the needed effect.
Actos Dosage
When prescribing you a dose, your therapist will take into consideration the following factors:
- The effectiveness of diabetes control
- Other disorders you suffer from
- Other drugs you use and other therapies you undergo.
Do not change the dosage unless you receive special instructions to do so from your healthcare provider.
Possible Side Effects of Therapy with Actos
Actos as any other drug is capable of producing side effects; however, the practice shows that a patient undergoing the therapy would not necessarily experience them. On the contrary, most patients if they happen to experience any side effects, go only through minor ones which can be easily treated by the patients themselves of by their healthcare provider. Serious side effects do not frequently take place.
It is obligatory for you also to make sure that your healthcare provider knows about all the other medications you're taking, either prescribed or non-prescribed, including vitamins and herbal supplements.
Is There Any Alternative to Therapy with Actos?
The basis of type 2 diabetes treatment is changing lifestyle (such as weight loss, exercise, and diet). If this still does not bring about any improvement at managing diabetes, the treatment with medications such as Actos may be necessary.
The drug in this case has the main aim of lowering the level of blood sugar as much as it is needed to reduce the chances of developing the diabetes caused problems, such as heart, nerve, eye or kidney dysfunctions of different kinds.
On average, Actos is quite effective and allows controlling the level of blood sugar. Most people tolerate it quite well. However there is always a possibility of developing side effects or something going wrong in the work of the drug. If something similar happens, you might need to combine Actos with some other drugs used to treat diabetes, for instance metformin (Glucophage®) or insulin or search for the alternative medicine able to serve as a substitute for Actos. Among the latter there might be thiazolidinediones or other diabetes medicines, either one or a combination of medicines.
What Should I Do in Case of Overdose with Actos?
The clinical studies have shown that usually the doses of Actos that equal at up to 180 mg do not provoke any side effects. Thus, the symptoms of overdosing with Actos are not yet found out. If you happen to take a huge dose, go for immediate professional medical help.
How Should I Store Actos?
The storage rules of Actos include storing it in an airtight container at room temperature away from humid and heated environments and keeping it out of children's reach.
What Strengths of Actos Are Available?
Actos is produced in several strengths, including:
- Actos 15 mg tablets
- Actos 30 mg tablets
- Actos 45 mg tablets.
Is Actos Available in the Form of a Generic Medication?
Generic form of Actos is not yet available for purchase.
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